Is Flow-Mediated Dilation Nitric Oxide Mediated?

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Is flow-mediated dilation nitric oxide mediated?: A meta-analysis.

Flow-mediated dilation (FMD) is a noninvasive index of endothelial function and vascular health in humans. Studies examining the role of nitric oxide (NO) are not conclusive. In this article, we quantified the contribution of NO in FMD of conduit arteries and explored the effect of the protocol (ie, distal cuff, ≈5-minute ischemia) and method of analysis (ie, automated and continuous edge detec...

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There's more to flow-mediated dilation than nitric oxide.

Flow-mediated dilation (FMD) is the standard tool used to assess endothelial function. The premise behind the standard FMD test is that it serves as an endothelial-dependant nitric oxide bioassay; however, the endothelium may release additional dilatory molecules which contribute to FMD, most notably prostacyclin and endothelial-derived hyperpolarizing factor. The relative importance of these m...

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Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function

Before you embark on this debate with my redoubtable Canadian friends, you may find it advisable to take something to minimize your cardiovascular risk. I recommend the sensible precaution of a bottle of excellent Australian Shiraz. Pour yourself a generous measure and take a few sips. Now, if your glass appears half full, you might agree that the abundance of flow-mediated dilatation (FMD) stu...

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Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function

Before you embark on this debate with my redoubtable Canadian friends, you may find it advisable to take something to minimize your cardiovascular risk. I recommend the sensible precaution of a bottle of excellent Australian Shiraz. Pour yourself a generous measure and take a few sips. Now, if your glass appears half full, you might agree that the abundance of flow-mediated dilatation (FMD) stu...

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Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function.

Before you embark on this debate with my redoubtable Canadian friends, you may find it advisable to take something to minimize your cardiovascular risk. I recommend the sensible precaution of a bottle of excellent Australian Shiraz. Pour yourself a generous measure and take a few sips. Now, if your glass appears half full, you might agree that the abundance of flow-mediated dilatation (FMD) stu...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2014

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.113.02044